Oral Submucous Fibrosis Case Series

Oral Potentially Malignant Disorders: “A group of disorders of varying etiologies, usually tobacco, characterized by mutagen associated, spontaneous or hereditary alterations or mutations in the genetic material of oral epithelial cells with or without clinical and histomorphological alterations that may lead to oral squamous cell carcinoma transformation”

Precancerous Lesions: “A morphologically altered tissue in which oral cancer is more likely to occur than in its apparently normal counterpart” Precancerous Condition: “A generalized state with a significantly increased risk of cancer”

Pindborg (1966) defined: “An insidious chronic disease affecting any part of the oral cavity and sometimes pharynx. Although occasionally preceded by and/or associated with vesicle formation, it is always associated with juxta-epithelial inflammatory reaction followed by fibroblastic changes of the lamina propria with epithelial atrophy leading to stiffness of the oral mucosa causing trismus and inability to eating”